Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28311171 | 0.92 | ALDH1A1 (0.41) | KDM4ECYP2D6CYP2C19ALDH1A1HTT | |
| SCHEMBL3810971 | 0.87 | KDM4E (0.40) | KDM4ECYP2D6CYP2C19ALDH1A1HTT | |
| SCHEMBL28311187 | 0.86 | KDM4E (0.38) | KDM4ECYP2D6CYP2C19ALDH1A1HTT | |
| SCHEMBL618251 | 0.86 | GPR119 (0.46) | KDM4ECYP2D6CYP2C19GAA | |
| SCHEMBL2417654 | 0.84 | NPC1 (0.47) | KDM4ECYP2D6CYP2C19ALDH1A1HTT | |
| SCHEMBL619527 | 0.81 | KDM4E (0.41) | KDM4ECYP2D6CYP2C19ALDH1A1HTT | |
| SCHEMBL28312092 | 0.80 | KDM4E (0.39) | KDM4ECYP2D6CYP2C19ALDH1A1HTT | |
| SCHEMBL28311301 | 0.80 | KDM4E (0.39) | KDM4ECYP2D6CYP2C19ALDH1A1HTT | |
| SCHEMBL3813432 | 0.79 | SIGMAR1 (0.39) | KDM4ECYP2D6CYP2C19ALDH1A1HTT | |
| SCHEMBL618037 | 0.78 | GPR119 (0.44) | KDM4EALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110115365-A | The adjusting that actinism receptor and relative ligand are carried out | 西诺米克斯公司 | 2019-08-13 | — | — | CN | disclosed |