Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24218974 | 0.76 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAHTTNPSR1 | |
| SCHEMBL19335436 | 0.76 | KCNN4 (0.43) | MAPTHDAC6ALDH1A1RAB9ANPC1 | |
| SCHEMBL15842090 | 0.74 | MAOB (0.46) | ALDH1A1TSHRHSD17B10USP2 | |
| SCHEMBL27835393 | 0.72 | L3MBTL1 (0.43) | ALDH1A1KDM4EKMT2AMEN1DRD2 | |
| SCHEMBL27981818 | 0.70 | CA12 (0.54) | MAPTKMT2ASMN1; SMN2LMNATP53 | |
| SCHEMBL10473874 | 0.69 | MAPT (0.53) | MAPTHDAC6ALDH1A1RAB9ANPC1 | |
| SCHEMBL10473931 | 0.68 | MAPT (0.51) | MAPTHDAC6ALDH1A1RAB9ANPC1 | |
| SCHEMBL10472444 | 0.68 | MAPT (0.51) | MAPTHDAC6ALDH1A1RAB9ANPC1 | |
| Trifluoroacetic Acid SCHEMBL28476450 | 0.68 | CA12 (0.58) | MAPTHDAC6ALDH1A1RAB9ANPC1 | |
| SCHEMBL10405261 | 0.68 | MAPT (0.50) | MAPTHDAC6ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167930-A | ROR gamma modulators | 百时美施贵宝公司 | 2019-08-23 | — | — | CN | disclosed |