Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | AS3MT | Q9HBK9 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28314041 | 0.77 | SGMS2 (0.42) | MAOBLMNAHPGDMAPTRAB9A | |
| SCHEMBL4452496 | 0.76 | MAOB (0.56) | MAOBAS3MTNSD2SQORLMNA | |
| SCHEMBL621853 | 0.74 | NPC1 (0.51) | MAOBAS3MTNSD2SQORLMNA | |
| SCHEMBL8316680 | 0.73 | MAOB (0.55) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL27488692 | 0.71 | HTR1A (0.61) | MAOBLMNAHPGDCYP1A2PTGS1 | |
| SCHEMBL5163381 | 0.71 | MAOB (0.51) | MAOBAS3MTNSD2SQORLMNA | |
| SCHEMBL8727263 | 0.71 | MAOB (0.50) | MAOBAS3MTHPGDTSHRGAA | |
| SCHEMBL14234135 | 0.71 | MAOB (0.44) | MAOBAS3MTNSD2SQORHPGD | |
| SCHEMBL1952637 | 0.69 | HTR1A (0.51) | LMNAHPGDCYP1A2PTGS1SLC6A2 | |
| SCHEMBL273100 | 0.68 | LMNA (0.61) | MAOBLMNACYP1A2PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110049969-A | Quinolines, preparation method and its medical usage | 恩瑞生物医药科技（上海）有限公司 | 2019-07-23 | — | — | CN | disclosed |