Purine

Purine

SCHEMBL28316629

NP(O)O.c1ncc2[nH]cnc2n1

nearest known ligand 0.43

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
KDM4E B2RXH2 1/20 0.43
RXFP1 Q9HBX9 1/20 0.38
PI4KA P42356 2/20 0.36
PI4K2B Q8TCG2 2/20 0.36
PI4K2A Q9BTU6 2/20 0.36
PI4KB Q9UBF8 2/20 0.36
LRRK2 Q5S007 2/20 0.36
LMNA P02545 1/20 0.36
DRD3 P35462 1/20 0.36
XDH P47989 1/20 0.36
CDK2 P24941 3/20 0.35
CCNT1 O60563 1/20 0.33
CDK1 P06493 1/20 0.33
CCNB1 P14635 1/20 0.33
CDK7 P50613 1/20 0.33
CDK9 P50750 1/20 0.33
CCNH P51946 1/20 0.33
G6PD P11413 1/20 0.32
METAP2 P50579 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Purine SCHEMBL28164598 0.88 ALDH1A1 (0.44) ALDH1A1KDM4ERXFP1PI4KAPI4K2B
Purine SCHEMBL3158 0.88
Purine SCHEMBL6421380 0.88 ALDH1A1 (0.47) ALDH1A1KDM4ERXFP1PI4KAPI4K2B
Purine SCHEMBL2120554 0.88 ALDH1A1 (0.47) ALDH1A1KDM4ERXFP1PI4KAPI4K2B
Purine SCHEMBL30862524 0.88
Purine SCHEMBL29365913 0.88
Purine SCHEMBL29703771 0.88 ALDH1A1 (0.47) ALDH1A1KDM4ERXFP1PI4KAPI4K2B
Purine SCHEMBL27575443 0.86 ALDH1A1 (0.42) ALDH1A1KDM4ERXFP1PI4KAPI4K2B
Purine SCHEMBL37120 0.86 ALDH1A1 (0.45) ALDH1A1KDM4ERXFP1PI4KAPI4K2B
Purine SCHEMBL619820 0.86 ALDH1A1 (0.45) ALDH1A1KDM4ERXFP1PI4KAPI4K2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110088113-A Composition and method for phosphoramidite and oligonucleotide synthesis 波涛生命科学有限公司 2019-08-02 CN disclosed