Methylene Chloride

Methylene Chloride

SCHEMBL28316865

CNCc1ccc(OC)cc1.ClCCl

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
PKM P14618 1/20 0.53
CHRM2 P08172 1/20 0.52
LTA4H P09960 1/20 0.50
NPC1 O15118 2/20 0.49
MAPT P10636 2/20 0.49
RAB9A P51151 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
MEN1 O00255 1/20 0.49
GAA P10253 1/20 0.49
KMT2A Q03164 1/20 0.49
IDO1 P14902 1/20 0.48
HTT P42858 1/20 0.47
LMNA P02545 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9831 0.94 ALDH1A1 (0.59) ALDH1A1PKMCHRM2LTA4HNPC1
Hydrochloric Acid SCHEMBL5057702 0.91 ALDH1A1 (0.57) ALDH1A1PKMCHRM2LTA4HNPC1
SCHEMBL254443 0.88 MAOB (0.55) ALDH1A1PKMCHRM2LTA4HNPC1
SCHEMBL28674781 0.82 LOXL2 (0.55) ALDH1A1PKMCHRM2LTA4HNPC1
SCHEMBL9587169 0.80 PKM (0.66) ALDH1A1PKMGAAHTTLMNA
SCHEMBL23330034 0.79 CHRM2 (0.61) ALDH1A1PKMCHRM2LTA4HNPC1
SCHEMBL22168912 0.79 ALDH1A1 (0.53) ALDH1A1PKMCHRM2LTA4HNPC1
SCHEMBL6634889 0.78 ALDH1A1 (0.57) ALDH1A1PKMCHRM2NPC1MAPT
SCHEMBL7346729 0.78 ALDH1A1 (0.61) ALDH1A1PKMCHRM2LTA4HNPC1
SCHEMBL121529 0.78 CHRM2 (0.70) ALDH1A1PKMCHRM2GAAIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110194770-A Peptide acyl arginine deiminase inhibitor and application thereof 南京药捷安康生物科技有限公司 2019-09-03 CN disclosed