Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831 | 0.94 | ALDH1A1 (0.59) | ALDH1A1PKMCHRM2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5057702 | 0.91 | ALDH1A1 (0.57) | ALDH1A1PKMCHRM2NPC1RAB9A | |
| Methylene Chloride SCHEMBL28316865 | 0.88 | ALDH1A1 (0.53) | ALDH1A1PKMCHRM2NPC1RAB9A | |
| SCHEMBL13184538 | 0.84 | KDM4E (0.59) | ALDH1A1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL28674781 | 0.82 | LOXL2 (0.55) | MAOBALDH1A1PKMCHRM2NPC1 | |
| SCHEMBL25986535 | 0.82 | LTA4H (0.71) | MAOBALDH1A1LTA4HIDO1ESR2 | |
| SCHEMBL22451382 | 0.82 | LTA4H (0.71) | MAOBALDH1A1LTA4HIDO1ESR2 | |
| SCHEMBL6059611 | 0.82 | LTA4H (0.71) | MAOBALDH1A1LTA4HIDO1ESR2 | |
| SCHEMBL10077131 | 0.82 | PRMT6 (0.61) | MAOBALDH1A1CHRM2HTT | |
| SCHEMBL9587169 | 0.80 | PKM (0.66) | ALDH1A1PKMGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230117680-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2023-04-20 | — | — | US | disclosed |
| US-9777320-B2 | Molecular adaptors for dye conjugates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2017-10-03 | — | — | US | disclosed |
| US-9499862-B2 | Phospholinked dye analogs with an amino acid linker | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-11-22 | — | — | US | disclosed |
| US-20150197794-A1 | Phospholinked Dye Analogs with an Amino Acid Linker | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-07-16 | — | — | US | disclosed |
| US-8993737-B2 | Phospholinked dye analogs with an amino acid linker | PACIFIC BIOSCIENCES, INC. (US) | 2015-03-31 | — | — | US | disclosed |
| US-20120058473-A1 | Molecular Adaptors for Dye Conjugates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120052507-A1 | PHOSPHOLINKED DYE ANALOGS WITH AN AMINO ACID LINKER | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| EP-1479671-B1 | Pyrimidinone compounds | SMITHKLINE BEECHAM PLC (GB) | 2009-05-27 | — | — | EP | disclosed |
| US-7115616-B2 | Pyrimidinone compounds | SMITHKLINE BEECHAM PLC (GB) | 2006-10-03 | — | — | US | disclosed |
| US-6953803-B1 | 1-[(N-(2-(diethylamino)ethyl)-N-(4-(4-trifluoromethylphenyl)benzyl)aminocarbonylmethyl)]-2-(4-fluorobenzyl)thio-5-(1-methyl-4-pyrazolylmethyl)pyrimidin-4-one; enzyme inhibitors of lipoprotein associated phospholipase A2 (Lp-PLA2); atherosclerosis | SMITHKLINE BEECHAM P.L.C. (GB) | 2005-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120052507-A1 | PHOSPHOLINKED DYE ANALOGS WITH AN AMINO ACID LINKER | CHAMP1, MTAP, INCENP | MAOB 4798/4885ALDH1A1 1938/4885PKM 1806/4885 |
| US-20230117680-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | PPID, PPIF, PPIL1 | MAOB 838/4885ALDH1A1 2173/4885PKM 699/4885 |
| US-20120058473-A1 | Molecular Adaptors for Dye Conjugates | ALKBH1, ALKBH5, ALKBH3 | MAOB 4717/4885ALDH1A1 1427/4885PKM 3443/4885 |
| US-20150197794-A1 | Phospholinked Dye Analogs with an Amino Acid Linker | INCENP, CHAMP1, PNKP | MAOB 4786/4885ALDH1A1 2694/4885PKM 702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.