Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | BLM | P54132 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TERT | O14746 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13792628 | 0.87 | KMT2A (0.47) | KMT2AMEN1BLMRAB9ANPC1 | |
| SCHEMBL16381321 | 0.77 | MAOA (0.48) | KMT2AMEN1BLMRAB9ANPC1 | |
| SCHEMBL12774935 | 0.76 | ALDH1A1 (0.48) | KMT2AMEN1BLMRAB9ANPC1 | |
| SCHEMBL12303283 | 0.76 | ALDH1A1 (0.48) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL8618279 | 0.76 | LMNA (0.48) | KMT2AMAPTALDH1A1HSD17B10LMNA | |
| SCHEMBL28010303 | 0.75 | MAOA (0.46) | KMT2AMEN1BLMRAB9ANPC1 | |
| SCHEMBL9701681 | 0.73 | LMNA (0.46) | KMT2AMAPTALDH1A1HSD17B10LMNA | |
| SCHEMBL28302475 | 0.73 | AKT2 (0.44) | KMT2ARAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL9701635 | 0.73 | LMNA (0.50) | KMT2AMAPTALDH1A1HSD17B10LMNA | |
| SCHEMBL28883541 | 0.72 | AKT2 (0.47) | KMT2ARAB9ANPC1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110092724-B | Preparation method of N, N-dimethyl-1-naphthylamine compound | 湖南大学 | 2021-08-31 | — | — | CN | disclosed |
| CN-110092724-A | A kind of preparation method of N, N- dimethyl-1-naphthylamine class compound | 湖南大学 | 2019-08-06 | — | — | CN | disclosed |