Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGFRL1 | Q5TC84 | 16/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 14/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 14/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 13/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2831902 | 0.77 | MAOA (0.51) | ALDH1A1HTTMAPK1 | |
| SCHEMBL21366177 | 0.77 | OGFRL1 (0.49) | OGFRL1OPRM1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL21366175 | 0.74 | OGFRL1 (0.46) | OGFRL1OPRM1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL1969712 | 0.72 | ALDH1A1 (0.45) | ALDH1A1MAPTSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL28330812 | 0.71 | MAPK1 (0.54) | OGFRL1OPRM1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL2783065 | 0.71 | ALDH1A1 (0.59) | OGFRL1OPRM1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL29724622 | 0.71 | ALDH1A1 (0.59) | OGFRL1OPRM1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL20206668 | 0.71 | ALDH1A1 (0.53) | OGFRL1OPRM1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL19861061 | 0.71 | OGFRL1 (0.53) | OGFRL1OPRM1OPRK1OPRD1ALDH1A1 | |
| SCHEMBL11873127 | 0.70 | HSD17B10 (0.65) | ALDH1A1MAPTSMN1; SMN2CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087768-A1 | USE OF 1-(AMINOALKYL)-3-QUINOXALINE-2-ONE DERIVATIVES FOR THE PREPARATION OF COMPOUNDS HAVING AN ANTIOXIDANT ACTION | PHAFAG AKTIENGESELLSCHAFT (LI) | 2001-04-04 | — | — | EP | claimed |
| WO-1999066931-A1 | USE OF 1-(AMINOALKYL)-3-QUINOXALINE-2-ONE DERIVATIVES FOR THE PREPARATION OF COMPOUNDS HAVING AN ANTIOXIDANT ACTION | PHAFAG AKTIENGESELLSCHAFT (LI) | 1999-12-29 | — | — | WO | claimed |
| EP-1087768-A1 | USE OF 1-(AMINOALKYL)-3-QUINOXALINE-2-ONE DERIVATIVES FOR THE PREPARATION OF COMPOUNDS HAVING AN ANTIOXIDANT ACTION | PHAFAG AKTIENGESELLSCHAFT (LI) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999066931-A1 | USE OF 1-(AMINOALKYL)-3-QUINOXALINE-2-ONE DERIVATIVES FOR THE PREPARATION OF COMPOUNDS HAVING AN ANTIOXIDANT ACTION | PHAFAG AKTIENGESELLSCHAFT (LI) | 1999-12-29 | — | — | WO | disclosed |