Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 3/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10794262 | 0.79 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL3104058 | 0.79 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL2842761 | 0.77 | LMNA (0.44) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL4263660 | 0.76 | MMP1 (0.30) | MMP2MMP1MMP3MMP8 | |
| Hydrochloric Acid SCHEMBL14778003 | 0.76 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| Iodide SCHEMBL14777842 | 0.76 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL754545 | 0.76 | MMP1 (0.39) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| Bromide SCHEMBL14777926 | 0.76 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL4265723 | 0.74 | PLA2G1B (0.32) | TSHRPLA2G1BDNM1 | |
| Fluoride SCHEMBL30636245 | 0.74 | LMNA (0.43) | ALDH1A1SMN1; SMN2LMNATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108828-A1 | SYNTHESIS OF DRONEDARONE AND SALTS THEREOF | USV Limited, B.S.D. Marg (IN) | 2012-05-03 | — | — | US | disclosed |
| EP-2428511-A1 | Synthesis of dronedarone and salts thereof | USV Limited (IN) | 2012-03-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108828-A1 | SYNTHESIS OF DRONEDARONE AND SALTS THEREOF | CYP3A4, CYP2D6, CYP3A43 | ALDH1A1 1001/4885SMN1; SMN2 3861/4885LMNA 740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.