Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4268208 | 0.91 | FDPS (0.33) | PLA2G1BPLA2G2AFDPS | |
| SCHEMBL4263660 | 0.88 | MMP1 (0.30) | — | |
| SCHEMBL4264064 | 0.87 | DNM1 (0.39) | PLA2G1BPLA2G2ADNM1TSHRTHRB | |
| SCHEMBL4265822 | 0.82 | DNM1 (0.37) | PLA2G1BPLA2G2ADNM1TSHRTHRB | |
| SCHEMBL17430697 | 0.76 | DNM1 (0.40) | PLA2G1BPLA2G2ADNM1TSHRTHRB | |
| SCHEMBL4413219 | 0.75 | FDPS (0.36) | FDPS | |
| SCHEMBL283202 | 0.74 | ALDH1A1 (0.39) | PLA2G1BDNM1TSHR | |
| SCHEMBL705999 | 0.71 | PLA2G1B (0.30) | PLA2G1BPLA2G2A | |
| SCHEMBL708082 | 0.70 | PLA2G1B (0.32) | PLA2G1BPLA2G2A | |
| SCHEMBL27032991 | 0.69 | MMP1 (0.32) | DNM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399570-B2 | Functionalized polymers and improved tires therefrom | BRIDGESTONE CORPORATION (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20090326161-A1 | FUNCTIONALIZED POLYMERS AND IMPROVED TIRES THEREFROM | BRIDGESTONE CORPORATION (JP) | 2009-12-31 | — | — | US | disclosed |
| US-7598322-B1 | particularly tire treads exhibiting reduced rolling resistance; a vulcanized rubbery polymer such as polybutadiene-butadiene-styrene copolymer made from living polymerization using butyllithium initiator and a tributyloxyborane as polymerization terminator | BRIDGESTONE CORPORATION (JP) | 2009-10-06 | — | — | US | disclosed |