Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 8/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.35 |
| ▸ | CYP21A2 | P08686 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28320551 | 0.81 | NFE2L2 (0.50) | NFE2L2PTGS1APP | |
| SCHEMBL28321741 | 0.80 | NQO2 (0.40) | NFE2L2PTGS1PTGS2NQO2ALOX5 | |
| SCHEMBL28320536 | 0.76 | IDO1 (0.49) | NFE2L2PTGS1PTGS2NQO2ALOX5 | |
| SCHEMBL28321690 | 0.74 | NFE2L2 (0.45) | NFE2L2PTGS1PTGS2NQO2ALOX5 | |
| SCHEMBL10648311 | 0.74 | KDM4E (0.36) | NFE2L2PTGS1PTGS2NQO2ALOX5 | |
| SCHEMBL10648278 | 0.74 | KDM4E (0.36) | NFE2L2PTGS1PTGS2NQO2ALOX5 | |
| SCHEMBL16399488 | 0.74 | NFE2L2 (0.39) | NFE2L2PTGS1PTGS2NQO2ALOX5 | |
| SCHEMBL16399489 | 0.74 | NFE2L2 (0.39) | NFE2L2PTGS1PTGS2NQO2ALOX5 | |
| SCHEMBL105252 | 0.72 | RAB9A (0.40) | ALOX5 | |
| SCHEMBL16399605 | 0.72 | NFE2L2 (0.40) | NFE2L2PTGS1PTGS2NQO2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408325-B | cyanotriazole compounds | 大塚制药株式会社 | 2019-10-22 | — | — | CN | disclosed |