Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 2/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9233259 | 0.89 | MAPT (0.49) | MAPTPIN1ALDH1A1KDM4EKMT2A | |
| SCHEMBL16398928 | 0.83 | KDM4E (0.57) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL5343234 | 0.80 | KDM4E (0.45) | ALDH1A1KDM4ECYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL8726514 | 0.80 | PTGER2 (0.46) | MAPTPTGER2LDHAPIN1ALDH1A1 | |
| SCHEMBL18002916 | 0.78 | SMN1; SMN2 (0.43) | MAPTPIN1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL16400081 | 0.78 | ALDH1A1 (0.50) | MAPTPIN1ALDH1A1KDM4EMEN1 | |
| SCHEMBL7110619 | 0.77 | MAPT (0.74) | MAPTALDH1A1MRGPRX4KDM4ECYP1A2 | |
| SCHEMBL2872521 | 0.77 | PTGS1 (0.48) | ALDH1A1KDM4EMEN1KMT2APPARG | |
| SCHEMBL11587313 | 0.75 | ALDH1A1 (0.61) | MAPTPIN1ALDH1A1MRGPRX4KDM4E | |
| SCHEMBL9669008 | 0.75 | MAPT (0.44) | MAPTPIN1ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408325-B | cyanotriazole compounds | 大塚制药株式会社 | 2019-10-22 | — | — | CN | disclosed |