Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9236648 | 0.88 | ICAM1 (0.46) | P2RX3PIN1LMNAL3MBTL1KDM4E | |
| SCHEMBL8722252 | 0.85 | MAPT (0.59) | PIN1LMNAL3MBTL1KDM4EMEN1 | |
| SCHEMBL5343234 | 0.84 | KDM4E (0.45) | P2RX3LMNAL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL11588419 | 0.82 | P2RX3 (0.55) | PTGER2LDHAP2RX3MAPTMRGPRX4 | |
| SCHEMBL8724307 | 0.82 | L3MBTL1 (0.57) | P2RX3LMNAL3MBTL1KDM4EMEN1 | |
| SCHEMBL28320654 | 0.80 | MAPT (0.50) | PTGER2LDHAPIN1L3MBTL1KDM4E | |
| SCHEMBL2872521 | 0.80 | PTGS1 (0.48) | P2RX3LMNAKDM4EMEN1ALDH1A1 | |
| SCHEMBL4355343 | 0.72 | TLR7 (0.64) | LDHALMNAL3MBTL1KDM4EMEN1 | |
| SCHEMBL2873881 | 0.72 | P2RX3 (0.42) | P2RX3LMNAIGFBP3XDHSLC22A12 | |
| SCHEMBL11412089 | 0.71 | HRH3 (0.54) | XDHSLC22A12RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700394-B1 | HERBICIDAL THIAZOLE DERIVATIVES | SHELL INT RESEARCH (NL) | 1998-04-01 | — | — | EP | disclosed |
| US-5693594-A | Herbicidal thiazole derivatives | AMERICAN CYANAMID COMPANY (US) | 1997-12-02 | — | — | US | disclosed |
| EP-0700394-A1 | HERBICIDAL THIAZOLE DERIVATIVES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027983-A1 | HERBICIDAL THIAZOLE DERIVATIVES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1994-12-08 | — | — | WO | disclosed |