Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.48 |
| ▸ | SELE | P16581 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28320654 | 0.89 | MAPT (0.50) | MAPTICAM1SELEALDH1A1KDM4E | |
| SCHEMBL16398928 | 0.82 | KDM4E (0.57) | MAPTALDH1A1KDM4EKMT2ACYP2C9 | |
| SCHEMBL9236648 | 0.81 | ICAM1 (0.46) | MAPTICAM1SELEALDH1A1CHEK2 | |
| SCHEMBL8569584 | 0.78 | MAPT (0.73) | MAPTICAM1SELEALDH1A1CHEK2 | |
| SCHEMBL16400081 | 0.77 | ALDH1A1 (0.50) | MAPTICAM1SELEALDH1A1F10 | |
| SCHEMBL18002916 | 0.77 | SMN1; SMN2 (0.43) | MAPTICAM1SELEALDH1A1F10 | |
| SCHEMBL9234917 | 0.76 | ICAM1 (0.49) | MAPTICAM1SELEALDH1A1CHEK2 | |
| SCHEMBL8722720 | 0.75 | MAPT (0.49) | MAPTICAM1SELEALDH1A1CHEK2 | |
| SCHEMBL3844011 | 0.75 | MAPT (0.58) | MAPTICAM1SELEALDH1A1CHEK2 | |
| SCHEMBL9669008 | 0.74 | MAPT (0.44) | MAPTICAM1SELEALDH1A1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700394-A1 | HERBICIDAL THIAZOLE DERIVATIVES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027983-A1 | HERBICIDAL THIAZOLE DERIVATIVES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1994-12-08 | — | — | WO | disclosed |