SCHEMBL28320666

SCHEMBL28320666

CC1(c2ccccc2)C[Si](C)(C)[Si](C)(C)[Si](C)(C)O1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 7/20 0.33
OPRM1 P35372 1/20 0.31
OPRK1 P41145 1/20 0.31
OPRL1 P41146 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18126 0.75 HSD11B1 (0.36) HSD11B1OPRM1OPRK1OPRL1
SCHEMBL5310275 0.73 HSD11B1 (0.31) HSD11B1
SCHEMBL7140516 0.72 MAOA (0.35) OPRM1OPRK1OPRL1
SCHEMBL7063060 0.70 CYP2D6 (0.30)
SCHEMBL29243150 0.68 MEN1 (0.33) OPRM1OPRK1OPRL1
SCHEMBL18143560 0.67 HSD11B1 (0.31) HSD11B1
SCHEMBL5647082 0.67 HSD11B1 (0.31) HSD11B1
SCHEMBL5552263 0.67 GRIN1 (0.31)
SCHEMBL9860049 0.67
SCHEMBL8733746 0.66 HSD11B1 (0.33) HSD11B1OPRM1OPRK1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110256960-B Organic silicon high-temperature-resistant coating and preparation method thereof 广东省科学院产业技术育成中心 2020-11-10 CN claimed
CN-110256960-B Organic silicon high-temperature-resistant coating and preparation method thereof 广东省科学院产业技术育成中心 2020-11-10 CN disclosed
CN-110256960-A A kind of high temperature organosilicon paint and preparation method thereof 广东省科学院产业技术育成中心 2019-09-20 CN disclosed