SCHEMBL18126

SCHEMBL18126

CC1(c2ccccc2)CC[Si](C)(C)[Si](C)(C)O1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 9/20 0.36
OPRM1 P35372 2/20 0.34
OPRK1 P41145 1/20 0.34
OPRL1 P41146 1/20 0.34
DRD2 P14416 1/20 0.30
SIGMAR1 Q99720 1/20 0.30
DRD4 P21917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1552116 0.81 OPRM1 (0.36) OPRM1OPRK1OPRL1DRD4
SCHEMBL8733746 0.79 HSD11B1 (0.33) HSD11B1OPRM1OPRK1OPRL1
SCHEMBL28320666 0.75 HSD11B1 (0.33) HSD11B1OPRM1OPRK1OPRL1
SCHEMBL3263252 0.75 HSD11B1 (0.36) HSD11B1OPRM1OPRK1OPRL1
SCHEMBL8736132 0.74 NFE2L2 (0.37) SIGMAR1
SCHEMBL28879224 0.73 OPRM1 (0.31) OPRM1OPRK1OPRL1
SCHEMBL17512349 0.72 HSD11B1 (0.35) HSD11B1OPRM1OPRK1OPRL1DRD2
SCHEMBL8405436 0.71 HSD11B1 (0.34) HSD11B1OPRM1OPRK1OPRL1
SCHEMBL6531179 0.71 HSD11B1 (0.34) HSD11B1OPRM1OPRK1OPRL1DRD2
SCHEMBL8767688 0.71 ALDH1A1 (0.34) HSD11B1OPRM1OPRL1DRD2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 386 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107235996-A A kind of preparation method and application of trimethyl silicane alkoxide 壮铭新材料科技江苏有限公司 2017-10-10 CN claimed
EP-1309306-A2 WATER-IN-OIL EMULSION COMPOSITIONS COMPRISING POLYALKYLENE GLYCOL STYLING AGENTS THE PROCTER & GAMBLE COMPANY (US) 2003-05-14 EP claimed
WO-2002011684-A2 WATER-IN-OIL EMULSION COMPOSITIONS COMPRISING POLYALKYLENE GLYCOL STYLING AGENTS THE PROCTER & GAMBLE COMPANY (US) 2002-02-14 WO claimed
US-6300027-B1 Low surface energy photoreceptors XEROX CORPORATION 2001-10-09 US claimed
JP-2001507372-A 2001-06-05 JP claimed
EP-0977540-A1 PERSONAL CARE COMPOSITIONS CONTAINING GRAFT POLYMERS THE PROCTER & GAMBLE COMPANY (US) 2000-02-09 EP claimed
WO-1998051261-A1 PERSONAL CARE COMPOSITIONS CONTAINING GRAFT POLYMERS THE PROCTER & GAMBLE COMPANY (US) 1998-11-19 WO claimed
EP-4635577-A2 WATER-RESISTANT AND/OR PHOTOPROTECTIVE COMPOSITIONS COMPRISING NON-SOLUBILIZED MICRONIZED WAXES Lubrizol Advanced Materials, Inc. (US) 2025-10-22 EP disclosed
EP-4044992-B1 WATER-RESISTANT AND/OR PHOTOPROTECTIVE COMPOSITIONS COMPRISING NON-SOLUBILIZED MICRONIZED WAXES LUBRIZOL ADVANCED MAT INC (US) 2025-09-17 EP disclosed
US-20250000778-A1 CHELANT AND CYCLODEXTRIN COMPOSITIONS COTY INC. 2025-01-02 US disclosed
WO-2024228461-A1 ANTIBACTERIAL COMPOSITION 한국콜마주식회사 2024-11-07 WO disclosed
EP-4415683-A1 CHELANT AND CYCLODEXTRIN COMPOSITIONS Coty Inc. (US) 2024-08-21 EP disclosed
US-12059490-B2 Avobenzone-dendrimer conjugates NEW YORK UNIVERSITY (US) 2024-08-13 US disclosed
EP-0412707-A1 Hair conditioning and styling compositions THE PROCTER & GAMBLE COMPANY (US) 1991-02-13 EP disclosed
EP-0412710-A2 Vehicle systems for use in cosmetic compositions THE PROCTER & GAMBLE COMPANY (US) 1991-02-13 EP disclosed
EP-0412704-A2 Hair conditioning and styling compositions THE PROCTER & GAMBLE COMPANY (US) 1991-02-13 EP disclosed
EP-0412706-A2 Vehicle systems for use in cosmetic compostions THE PROCTER & GAMBLE COMPANY (US) 1991-02-13 EP disclosed
EP-0323715-A2 Hair styling agents and compositions containing the same THE PROCTER & GAMBLE COMPANY (US) 1989-07-12 EP disclosed
EP-0320218-A2 Low glass transition temperature adhesive copolymers for use in hair styling products THE PROCTER & GAMBLE COMPANY (US) 1989-06-14 EP disclosed
US-4247674-A Use of bis(fluoroaliphaticsulfonyl)imides in polymerization of organocyclosiloxanes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12059490-B2 Avobenzone-dendrimer conjugates ASPH, DDT, SUCLG1 HSD11B1 2318/4885OPRM1 4281/4885OPRK1 3080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.