Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18126 | 0.79 | HSD11B1 (0.36) | HSD11B1OPRM1OPRK1OPRL1 | |
| SCHEMBL912511 | 0.72 | — | — | |
| SCHEMBL6560369 | 0.71 | — | — | |
| SCHEMBL3263252 | 0.69 | HSD11B1 (0.36) | HSD11B1OPRM1OPRK1OPRL1 | |
| SCHEMBL17559157 | 0.68 | — | — | |
| SCHEMBL8461705 | 0.68 | ALDH1A1 (0.34) | HSD11B1 | |
| SCHEMBL11700256 | 0.68 | OPRM1 (0.31) | OPRM1OPRK1OPRL1 | |
| SCHEMBL17512349 | 0.67 | HSD11B1 (0.35) | HSD11B1OPRM1OPRK1OPRL1 | |
| SCHEMBL27605394 | 0.67 | OPRM1 (0.30) | OPRM1OPRK1OPRL1 | |
| SCHEMBL28320666 | 0.66 | HSD11B1 (0.33) | HSD11B1OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693089-B1 | ORGANOSILICON-CONTAINING MATERIALS USEFUL FOR BIOMEDICAL DEVICES | BAUSCH & LOMB (US) | 1998-07-29 | — | — | EP | disclosed |
| US-5616757-A | CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 1997-04-01 | — | — | US | disclosed |
| US-5510442-A | SOFT CONTACT LENSES; OXYGEN PERMEABILITY | BAUSCH & LOMB INCORPORATED (US) | 1996-04-23 | — | — | US | disclosed |
| EP-0693089-A1 | ORGANOSILICON-CONTAINING MATERIALS USEFUL FOR BIOMEDICAL DEVICES | BAUSCH & LOMB INCORPORATED (US) | 1996-01-24 | — | — | EP | disclosed |
| WO-1994024187-A2 | ORGANOSILICON-CONTAINING MATERIALS USEFUL FOR BIOMEDICAL DEVICES | BAUSCH & LOMB INCORPORATED (US) | 1994-10-27 | — | — | WO | disclosed |