Formaldehyde

Formaldehyde

SCHEMBL28320754

C1=Nc2ccccc2CN1.C1=Nc2ccccc2CN1.C=O

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 5/20 0.37
NPC1 O15118 1/20 0.37
HPGD P15428 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
PARP1 P09874 1/20 0.34
NOS3 P29474 1/20 0.34
NOS1 P29475 1/20 0.34
NOS2 P35228 1/20 0.34
PNMT P11086 1/20 0.33
CD44 P16070 1/20 0.33
MAOB P27338 1/20 0.33
HTR2C P28335 1/20 0.32
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PDE3B Q13370 1/20 0.31
PDE3A Q14432 1/20 0.31
PLAU P00749 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29546867 0.94 TRPA1 (0.41) TRPA1NPC1HPGDRAB9ASMN1; SMN2
SCHEMBL1398081 0.94 TRPA1 (0.41) TRPA1NPC1HPGDRAB9ASMN1; SMN2
Water SCHEMBL28834494 0.92 TRPA1 (0.39) TRPA1NPC1HPGDRAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL30528593 0.92 NPC1 (0.43) TRPA1NPC1HPGDRAB9ASMN1; SMN2
SCHEMBL30843932 0.78
SCHEMBL11034734 0.73 TRPA1 (0.38) TRPA1NPC1HPGDRAB9ASMN1; SMN2
SCHEMBL7977488 0.71 MEN1 (0.35)
SCHEMBL30874783 0.71 MEN1 (0.35)
SCHEMBL16479002 0.68 CA12 (0.36) PARP1PNMTCD44MAOBCA12
SCHEMBL3427220 0.68 CHRNB2 (0.42) HTR2CPDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104865796-B Colored curable resin composition 东友精细化工有限公司 2019-11-08 CN disclosed
CN-110272392-A Transition metal catalyzed C-H coupling for efficiently preparing 2- (4(3H) -quinazolinone) aryl alkyl acetate derivative 四川大学 2019-09-24 CN disclosed