Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GRK6 | P43250 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.30 |
| ▸ | HTR3B | O95264 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | HTR5A | P47898 | 1/20 | 0.30 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.30 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874783 | 1.00 | MEN1 (0.35) | MEN1KMT2AGRK6NQO2HTR3E | |
| SCHEMBL29546867 | 0.75 | TRPA1 (0.41) | GRK6 | |
| SCHEMBL1398081 | 0.75 | TRPA1 (0.41) | GRK6 | |
| Hydrochloric Acid SCHEMBL30528593 | 0.74 | NPC1 (0.43) | MEN1KMT2AGRK6 | |
| Water SCHEMBL28834494 | 0.74 | TRPA1 (0.39) | GRK6 | |
| SCHEMBL29484156 | 0.72 | — | — | |
| Formaldehyde SCHEMBL28320754 | 0.71 | TRPA1 (0.37) | — | |
| SCHEMBL7206323 | 0.69 | MEN1 (0.39) | MEN1KMT2ANQO2HTR3A | |
| SCHEMBL15120307 | 0.69 | HTR5A (0.35) | HTR5A | |
| SCHEMBL29809502 | 0.69 | CYP2D6 (0.33) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207667-B1 | USEFUL FOR THE TREATMENT OF CELL-PROLIFERATIVE DISEASES SUCH AS ARTERIOSCLEROSIS, VASCULAR REOBSTRUCTION, CANCER AND GLOMERULOSCLEROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |