Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | CD44 | P16070 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29546867 | 0.78 | TRPA1 (0.41) | TRPA1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL1398081 | 0.78 | TRPA1 (0.41) | TRPA1NPC1HPGDRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30528593 | 0.77 | NPC1 (0.43) | TRPA1NPC1HPGDRAB9ASMN1; SMN2 | |
| Water SCHEMBL28834494 | 0.77 | TRPA1 (0.39) | TRPA1NPC1HPGDRAB9ASMN1; SMN2 | |
| Formaldehyde SCHEMBL28320754 | 0.73 | TRPA1 (0.37) | TRPA1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7532560 | 0.70 | NOS3 (0.33) | TRPA1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL29412494 | 0.67 | PNMT (0.39) | TRPA1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL17080875 | 0.67 | PNMT (0.39) | TRPA1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL29374426 | 0.66 | PNMT (0.50) | PNMTCD44MAOBHTR2CALOX15 | |
| SCHEMBL214465 | 0.66 | PNMT (0.50) | PNMTCD44MAOBHTR2CALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035228-B1 | TETRAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND ANTI-ULCER COMPOSITION CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-01-02 | — | — | EP | claimed |