Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 13/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | MGAM | O43451 | 6/20 | 0.56 |
| ▸ | SI | P14410 | 6/20 | 0.56 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2540914 | 0.82 | ALDH1A1 (0.53) | GAAKDM4EALDH1A1MGAMSI | |
| SCHEMBL1230426 | 0.82 | GAA (1.00) | GAAKDM4EALDH1A1MGAMSI | |
| SCHEMBL27752820 | 0.77 | HSD17B3 (0.60) | GAAKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL27752675 | 0.77 | KDM4E (0.62) | KDM4EALDH1A1LMNAMAPTNQO1 | |
| SCHEMBL7483002 | 0.77 | GAA (0.69) | GAAKDM4EALDH1A1MGAMSI | |
| SCHEMBL94134 | 0.77 | GAA (0.69) | GAAKDM4EALDH1A1MGAMSI | |
| SCHEMBL6810405 | 0.77 | GAA (0.69) | GAAKDM4EALDH1A1MGAMSI | |
| SCHEMBL21035694 | 0.75 | KDM4E (0.55) | GAAKDM4EALDH1A1MGAMSI | |
| SCHEMBL9499096 | 0.74 | GAA (0.65) | GAAKDM4EALDH1A1MGAMSI | |
| SCHEMBL30014125 | 0.74 | GAA (0.65) | GAAKDM4EALDH1A1MGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110283181-A | A kind of method of synthesizing coumarin [4,3-d] pyrimidine derivatives | 长沙理工大学 | 2019-09-27 | — | — | CN | disclosed |