Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27752820 | 0.82 | HSD17B3 (0.60) | ALDH1A1KDM4EGAAMAPTLMNA | |
| SCHEMBL27752675 | 0.82 | KDM4E (0.62) | ALDH1A1KDM4EMAPTLMNASMN1; SMN2 | |
| SCHEMBL28320998 | 0.82 | GAA (0.69) | ALDH1A1KDM4EGAAMAPTLMNA | |
| SCHEMBL5273182 | 0.79 | CA9 (0.53) | ALDH1A1KDM4EGAAMAPTLMNA | |
| SCHEMBL28004955 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KDM4EGAAMAPTLMNA | |
| SCHEMBL28091429 | 0.76 | PLA2G2A (0.53) | KDM4EADORA3MEN1KMT2ANQO1 | |
| SCHEMBL30272141 | 0.76 | LMNA (0.67) | ALDH1A1GAAMAPTLMNAHTT | |
| SCHEMBL2017838 | 0.76 | LMNA (0.67) | ALDH1A1GAAMAPTLMNAHTT | |
| SCHEMBL15842804 | 0.75 | AHR (0.50) | ALDH1A1KDM4EGAALMNATDP1 | |
| SCHEMBL10336569 | 0.75 | NQO1 (0.56) | ALDH1A1KDM4EHSD17B10HPGDMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118791455-A | Synthetic method for preparing 3, 4-dichloro coumarin from 4-chloro coumarin | 广西大学 | 2024-10-18 | — | — | CN | claimed |
| CN-105884739-B | A kind of synthetic method of benzo cumarin polycyclic compound | 广西大学 | 2018-04-27 | — | — | CN | claimed |
| CN-105884739-A | Synthetic method for benzocoumarin polycyclic compounds | 广西大学 | 2016-08-24 | — | — | CN | claimed |
| US-9127092-B2 | Method for producing polydienes and polydiene copolymers with reduced cold flow | BRIDGESTONE CORPORATION (JP) | 2015-09-08 | — | — | US | claimed |
| US-20140187725-A1 | METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2014-07-03 | — | — | US | claimed |
| CN-118791455-B | Synthetic method for preparing 3, 4-dichloro coumarin from 4-chloro coumarin | 广西大学 | 2025-09-30 | — | — | CN | disclosed |
| CN-118791455-B | Synthetic method for preparing 3, 4-dichloro coumarin from 4-chloro coumarin | 广西大学 | 2025-09-30 | — | — | CN | disclosed |
| CN-118791455-A | Synthetic method for preparing 3, 4-dichloro coumarin from 4-chloro coumarin | 广西大学 | 2024-10-18 | — | — | CN | disclosed |
| CN-118791455-A | Synthetic method for preparing 3, 4-dichloro coumarin from 4-chloro coumarin | 广西大学 | 2024-10-18 | — | — | CN | disclosed |
| CN-118791455-A | Synthetic method for preparing 3, 4-dichloro coumarin from 4-chloro coumarin | 广西大学 | 2024-10-18 | — | — | CN | disclosed |
| US-11400062-B2 | Compositions comprising enzyme-cleavable amphetamine prodrugs and inhibitors thereof | SIGNATURE THERAPEUTICS, INC. (US) | 2022-08-02 | — | — | US | disclosed |
| US-20220054479-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2022-02-24 | — | — | US | disclosed |
| US-20060142171-A1 | Novel alkaline protease | FORSKARPATENT I SYD AB (SE) | 2006-06-29 | — | — | US | disclosed |
| EP-1611235-A1 | NOVEL ALKALINE PROTEASE | Forskarpatent i Syd AB (SE) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004085639-A9 | NOVEL ALKALINE PROTEASE | FORSKARPATENT I SYD AB (SE) | 2005-11-10 | — | — | WO | disclosed |
| US-6916824-B1 | Methods of treating cataracts and diabetic retinopathy with tricyclic pyrones | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2005-07-12 | — | — | US | disclosed |
| WO-2004085639-A1 | NOVEL ALKALINE PROTEASE | FORSKARPATENT I SYD AB (SE) | 2004-10-07 | — | — | WO | disclosed |
| CN-1039967-C | Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes, 3-aminochromanes, and 3-aminothiochromanes | LILLY CO ELI (US) | 1998-09-30 | — | — | CN | disclosed |
| EP-0615548-A1 | NOVEL PROTEASES WITH DNA FRAGMENTING ACTIVITY | UNIVERSITY OF MANITOBA (CA) | 1994-09-21 | — | — | EP | disclosed |
| WO-1993011246-A1 | NOVEL PROTEASES WITH DNA FRAGMENTING ACTIVITY | UNIVERSITY OF MANITOBA (CA) | 1993-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220054479-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | OPRM1, OPRK1, OPRD1 | ALDH1A1 383/4885KDM4E 1535/4885GAA 82/4885 |
| US-11400062-B2 | Compositions comprising enzyme-cleavable amphetamine prodrugs and inhibitors thereof | ACHE, COMT, CES2 | ALDH1A1 795/4885KDM4E 812/4885GAA 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.