Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 10/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28321673 | 0.80 | NFE2L2 (0.51) | NFE2L2PTGS1 | |
| SCHEMBL28321694 | 0.78 | NQO2 (0.40) | NFE2L2PTGS1PTGS2ALOX5NQO2 | |
| SCHEMBL28321698 | 0.74 | NFE2L2 (0.44) | NFE2L2PTGS1PTGS2ALOX5NQO2 | |
| SCHEMBL28320536 | 0.74 | IDO1 (0.49) | NFE2L2PTGS1PTGS2ALOX5NQO2 | |
| SCHEMBL5020203 | 0.73 | POLB (0.48) | APP | |
| SCHEMBL16399605 | 0.73 | NFE2L2 (0.40) | NFE2L2PTGS1PTGS2ALOX5NQO2 | |
| SCHEMBL16399607 | 0.73 | NFE2L2 (0.40) | NFE2L2PTGS1PTGS2ALOX5NQO2 | |
| SCHEMBL16399489 | 0.72 | NFE2L2 (0.39) | NFE2L2PTGS1PTGS2ALOX5NQO2 | |
| SCHEMBL16399488 | 0.72 | NFE2L2 (0.39) | NFE2L2PTGS1PTGS2ALOX5NQO2 | |
| SCHEMBL28320604 | 0.69 | TUBB1 (0.55) | PTGS2NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408325-B | cyanotriazole compounds | 大塚制药株式会社 | 2019-10-22 | — | — | CN | disclosed |