Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.49 |
| ▸ | METAP2 | P50579 | 5/20 | 0.49 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28320616 | 0.81 | IDO1 (0.63) | IDO1METAP2NFE2L2KEAP1NOTUM | |
| SCHEMBL28321695 | 0.79 | IDO1 (0.41) | IDO1METAP2NFE2L2PHF8MAPK14 | |
| SCHEMBL28321698 | 0.76 | NFE2L2 (0.44) | NFE2L2PTGS1ALOX5PTGS2NQO2 | |
| SCHEMBL16399197 | 0.74 | ERBB2 (0.58) | NFE2L2PTGS1ALOX5PTGS2NQO2 | |
| SCHEMBL16399196 | 0.74 | ERBB2 (0.58) | NFE2L2PTGS1ALOX5PTGS2NQO2 | |
| SCHEMBL28321690 | 0.74 | NFE2L2 (0.45) | NFE2L2PTGS1ALOX5PTGS2NQO2 | |
| SCHEMBL104083 | 0.72 | METAP2 (0.64) | IDO1METAP2METAP1PHF8MAPK14 | |
| SCHEMBL28321705 | 0.69 | IDO1 (0.48) | IDO1NFE2L2PHF8PTGS1PTGS2 | |
| SCHEMBL16399488 | 0.69 | NFE2L2 (0.39) | NFE2L2PTGS1ALOX5PTGS2NQO2 | |
| SCHEMBL16399489 | 0.69 | NFE2L2 (0.39) | NFE2L2PTGS1ALOX5PTGS2NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408325-B | cyanotriazole compounds | 大塚制药株式会社 | 2019-10-22 | — | — | CN | disclosed |