Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28322179 | 0.75 | CYP1A2 (0.44) | CYP1A2CYP2D6AAK1MEN1CYP2C19 | |
| SCHEMBL7951407 | 0.74 | SLC6A4 (0.40) | CYP2D6MEN1KMT2A | |
| SCHEMBL3594428 | 0.73 | CYP2C19 (0.41) | CYP1A2CYP2D6MEN1CYP2C19KMT2A | |
| SCHEMBL2949855 | 0.71 | CYP2C9 (0.44) | MEN1KMT2A | |
| SCHEMBL8911121 | 0.71 | CYP2C9 (0.44) | MEN1KMT2A | |
| SCHEMBL28302645 | 0.70 | AAK1 (0.40) | CYP1A2CYP2D6AAK1 | |
| SCHEMBL28302644 | 0.70 | AAK1 (0.40) | CYP1A2CYP2D6AAK1 | |
| SCHEMBL13606606 | 0.65 | RAB9A (0.37) | CYP1A2AAK1MEN1KMT2A | |
| SCHEMBL28070918 | 0.64 | ACE (0.53) | — | |
| SCHEMBL28070907 | 0.64 | ACE (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110279872-A | Conjugated body of the cytotoxic molecule with cell bound receptor molecule | 杭州多禧生物科技有限公司 | 2019-09-27 | — | — | CN | disclosed |