Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2949855 | 1.00 | CYP2C9 (0.44) | CYP2C9USP30PAX8MEN1RAB9A | |
| SCHEMBL3594428 | 0.91 | CYP2C19 (0.41) | PAX8MEN1RAB9AKMT2ANPSR1 | |
| SCHEMBL7951407 | 0.82 | SLC6A4 (0.40) | MEN1RAB9AKMT2ANPSR1CTSS | |
| SCHEMBL1691044 | 0.75 | PAX8 (0.60) | USP30PAX8MEN1RAB9AKMT2A | |
| SCHEMBL16863750 | 0.75 | CYP2C9 (0.41) | CYP2C9USP30PAX8MEN1RAB9A | |
| SCHEMBL8720981 | 0.73 | MAPT (0.42) | CYP2C9KDM4EUSP2ALDH1A1MAPT | |
| SCHEMBL2460578 | 0.73 | KMT2A (0.39) | CYP2C9PAX8MEN1RAB9AKMT2A | |
| SCHEMBL27221203 | 0.73 | KMT2A (0.39) | CYP2C9PAX8MEN1RAB9AKMT2A | |
| SCHEMBL3621683 | 0.73 | KMT2A (0.39) | CYP2C9PAX8MEN1RAB9AKMT2A | |
| SCHEMBL9728563 | 0.72 | GBA1 (0.39) | PAX8CTSSCTSKALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | disclosed |