Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | SGK1 | O00141 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3594428 | 0.84 | CYP2C19 (0.41) | SLC6A4CYP2D6MEN1KMT2ARAB9A | |
| SCHEMBL2498935 | 0.82 | ALDH1A1 (0.40) | SLC6A4CYP3A4CYP2D6SLC6A2SLC6A3 | |
| SCHEMBL8911121 | 0.82 | CYP2C9 (0.44) | MEN1KMT2ARAB9ANPSR1CTSS | |
| SCHEMBL2949855 | 0.82 | CYP2C9 (0.44) | MEN1KMT2ARAB9ANPSR1CTSS | |
| SCHEMBL6324696 | 0.77 | FABP5 (0.41) | SLC6A4CYP3A4CYP2D6SLC6A2SLC6A3 | |
| SCHEMBL8721672 | 0.76 | CYP3A4 (0.39) | SLC6A4CYP3A4CYP2D6SLC6A2SLC6A3 | |
| SCHEMBL4065816 | 0.75 | APP (0.43) | KMT2ACTSBCTSSCTSKGABRB1 | |
| SCHEMBL4678770 | 0.74 | PTPN1 (0.49) | SLC6A4CYP3A4CYP2D6SLC6A2SLC6A3 | |
| SCHEMBL28322112 | 0.74 | CYP1A2 (0.43) | CYP2D6MEN1KMT2A | |
| SCHEMBL31453143 | 0.73 | PAX8 (0.51) | CYP3A4MEN1KMT2ARAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274584-B1 | PEPTIDE DERIVATIVES; BIOAVAILABILITY; ENZYME RESISTANCE; MILK AND WOOL PRODUCTION | NOVO NORDISK A/S (DK) | 2001-08-14 | — | — | US | disclosed |