Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | GRM5 | P41594 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28322328 | 0.88 | AKR1C3 (0.54) | MEN1KMT2ASMN1; SMN2ALDH1A1GRM5 | |
| SCHEMBL27857403 | 0.87 | HTR1A (0.50) | MEN1KMT2ASMN1; SMN2ALDH1A1GRM5 | |
| SCHEMBL10282747 | 0.86 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2ALDH1A1HTR1A | |
| SCHEMBL27662780 | 0.84 | AGXT (0.56) | SMN1; SMN2ALDH1A1MAPTSIGMAR1LMNA | |
| SCHEMBL8245954 | 0.81 | MAPT (0.70) | MEN1KMT2ASMN1; SMN2ALDH1A1GRM5 | |
| SCHEMBL27468903 | 0.80 | AGXT (0.49) | HTR1AHTR7HTR2AHTR6SIGMAR1 | |
| SCHEMBL28322327 | 0.79 | AGXT (0.46) | SMN1; SMN2ALDH1A1GRM5MAPTSIGMAR1 | |
| SCHEMBL689414 | 0.79 | GPR119 (0.56) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL13063408 | 0.78 | AGXT (0.46) | SMN1; SMN2ALDH1A1GRM5HTR1AHTR7 | |
| SCHEMBL27642212 | 0.78 | LMNA (0.47) | MEN1KMT2ASMN1; SMN2ALDH1A1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022178030-A1 | TRPM8 AGONISTS AS COOLING AGENTS AND FOR THE TREATMENT OF DISEASE | Concentric Analgesics, Inc. (US) | 2022-08-25 | — | — | WO | disclosed |