Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28079595 | 0.68 | MAOA (0.38) | MAOAMAOBHSD11B1TSHR | |
| SCHEMBL70588 | 0.63 | ALDH1A1 (0.38) | MAOAMAOBOPRL1HSD11B1OPRM1 | |
| SCHEMBL28199313 | 0.62 | MAOA (0.32) | MAOAMAOBTSHR | |
| SCHEMBL27461993 | 0.62 | MAOA (0.36) | MAOAMAOBOPRL1HSD11B1OPRM1 | |
| SCHEMBL9137089 | 0.61 | HSD11B1 (0.38) | MAOAMAOBOPRL1HSD11B1OPRM1 | |
| SCHEMBL8994429 | 0.60 | CYP3A4 (0.35) | MAOAMAOBHSD11B1TSHR | |
| Hydrochloric Acid SCHEMBL10323375 | 0.59 | MAOA (0.40) | MAOAMAOBOPRL1HSD11B1OPRM1 | |
| SCHEMBL5509298 | 0.58 | MAOA (0.35) | MAOAMAOBOPRL1OPRM1OPRD1 | |
| SCHEMBL23343753 | 0.58 | OPRL1 (0.65) | MAOAMAOBOPRL1OPRM1OPRD1 | |
| SCHEMBL9439377 | 0.58 | MAOA (0.48) | MAOAMAOBOPRL1HSD11B1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105916843-B | Octahydrocyclopenta [ c ] pyrrole selective NR2B negative regulator | 科登特治疗公司 | 2019-09-20 | — | — | CN | disclosed |