Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28080378 | 0.79 | CA1 (0.45) | CYP3A4KCNH2TDP1MAPT | |
| SCHEMBL30916838 | 0.78 | CA12 (0.46) | FFAR4CYP2C9GPR3 | |
| SCHEMBL29554405 | 0.77 | FFAR4 (0.41) | FFAR4FFAR1SCN5ACYP2C9GPR3 | |
| SCHEMBL3993839 | 0.77 | FFAR4 (0.41) | FFAR4FFAR1SCN5ACYP2C9GPR3 | |
| SCHEMBL14237634 | 0.77 | GPR3 (0.41) | FFAR4FFAR1SCN5ACYP2C9GPR3 | |
| SCHEMBL27705367 | 0.77 | PDE2A (0.41) | CYP2C9MRGPRX4CYP3A4KCNH2MAPT | |
| SCHEMBL28128499 | 0.76 | GPR3 (0.44) | FFAR4FFAR1SCN5AGPR3 | |
| SCHEMBL29177450 | 0.76 | FFAR4 (0.43) | FFAR4FFAR1SCN5ACYP2C9AKR1C2 | |
| SCHEMBL29894167 | 0.75 | GPR3 (0.48) | FFAR4FFAR1SCN5ACYP2C9GPR3 | |
| SCHEMBL8065084 | 0.75 | GPR3 (0.48) | FFAR4FFAR1SCN5ACYP2C9GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110337295-A | Compounds and methods of their use | 普拉克西斯精密药物股份有限公司 | 2019-10-15 | — | — | CN | disclosed |