SCHEMBL30916838

SCHEMBL30916838

COc1cc(OC(F)(F)F)ccc1OB(O)O

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
RUNX1 Q01196 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
ALPL P05186 3/20 0.39
GRM7 Q14831 2/20 0.39
MCHR1 Q99705 1/20 0.39
GPR3 P46089 1/20 0.39
ABL1 P00519 2/20 0.38
FFAR4 Q5NUL3 1/20 0.38
SCN8A Q9UQD0 1/20 0.38
SCN10A Q9Y5Y9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12422184 0.86 CA12 (0.61) CA12CA1CA2CA7CA9
SCHEMBL2936012 0.84 CA12 (0.65) CA12CA1CA2CA7CA9
SCHEMBL30702417 0.84 CA12 (0.65) CA12CA1CA2CA7CA9
SCHEMBL4048673 0.81 ENPP2 (0.44) CA12CA1CA2CA7CA9
SCHEMBL29956393 0.81 TUBB4A (0.46) CA12CA1CA2CA7CA9
SCHEMBL320667 0.81 TUBB4A (0.46) CA12CA1CA2CA7CA9
SCHEMBL29956187 0.81 ENPP2 (0.44) CA12CA1CA2CA7CA9
SCHEMBL28128499 0.81 GPR3 (0.44) GPR3FFAR4SCN8ASCN10A
SCHEMBL2178296 0.78 CA2 (0.61) CA12CA1CA2CA7CA9
SCHEMBL5748457 0.78 CA12 (0.47) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113272285-B Oxadiazole-containing compound and pharmaceutical composition containing same 爱思开生物制药株式会社 2024-06-07 CN disclosed