SCHEMBL28329261

SCHEMBL28329261

CCCc1ccccc1/C(C)=C/C=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
LMNA P02545 2/20 0.38
HCRTR1 O43613 4/20 0.37
HCRTR2 O43614 4/20 0.37
FOLH1 Q04609 1/20 0.36
KDR P35968 1/20 0.35
HTT P42858 2/20 0.34
CTSL P07711 1/20 0.34
CTSS P25774 1/20 0.34
CTSK P43235 1/20 0.34
PRKCI P41743 1/20 0.33
TP53 P04637 1/20 0.33
KDM4E B2RXH2 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KMT2A Q03164 1/20 0.33
DAO P14920 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28221235 0.81 PNMT (0.35) ALDH1A1LMNAFOLH1KDM4ESMN1; SMN2
SCHEMBL6546466 0.76 MEN1 (0.41) ALDH1A1LMNAFOLH1HTTSMN1; SMN2
SCHEMBL6546483 0.76 MEN1 (0.41) ALDH1A1LMNAFOLH1HTTSMN1; SMN2
SCHEMBL2125820 0.76 ALDH1A1 (0.47) ALDH1A1LMNAHCRTR1HCRTR2FOLH1
SCHEMBL30628269 0.76 ALDH1A1 (0.47) ALDH1A1LMNAHCRTR1HCRTR2FOLH1
SCHEMBL9046425 0.75 ALDH1A1 (0.42) ALDH1A1LMNAHCRTR1HCRTR2FOLH1
SCHEMBL18378183 0.75 ALDH1A1 (0.42) ALDH1A1LMNAHCRTR1HCRTR2FOLH1
SCHEMBL23367957 0.75 LMNA (0.34) ALDH1A1LMNAHCRTR1HCRTR2FOLH1
SCHEMBL9626488 0.74 FOLH1 (0.47) ALDH1A1LMNAHCRTR1HCRTR2FOLH1
SCHEMBL2491587 0.73 FOLH1 (0.41) ALDH1A1LMNAHCRTR1HCRTR2FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110494413-A Reduce the compound and application thereof of stench perception CHEMCOM SA 2019-11-22 CN disclosed