SCHEMBL28329593

SCHEMBL28329593

Cc1ccc(OC(=O)CC(C)c2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
ACHE P22303 1/20 0.50
HPGD P15428 2/20 0.47
LTB4R Q15722 1/20 0.47
LTB4R2 Q9NPC1 1/20 0.47
LMNA P02545 2/20 0.46
STAT3 P40763 1/20 0.46
GAA P10253 1/20 0.46
FNTA P49354 1/20 0.45
FNTB P49356 1/20 0.45
KMT2A Q03164 2/20 0.44
ELANE P08246 1/20 0.44
ALOX5 P09917 1/20 0.44
PTGS1 P23219 1/20 0.44
FFAR1 O14842 1/20 0.43
MEN1 O00255 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9794842 0.92 ALDH1A1 (0.50) ALDH1A1HPGDLTB4RLTB4R2ELANE
SCHEMBL27698503 0.87 ALDH1A1 (0.47) ALDH1A1HPGDLTB4RLTB4R2LMNA
SCHEMBL6180016 0.86 ELANE (0.50) ALDH1A1LTB4RLTB4R2KMT2AELANE
SCHEMBL1532609 0.81 LMNA (0.53) ALDH1A1ACHELMNAGAAKMT2A
SCHEMBL13626199 0.81 ALDH1A1 (0.56) ALDH1A1LMNAGAAKMT2AELANE
SCHEMBL10335682 0.78 ALDH1A1 (0.54) ALDH1A1HPGDLMNAGAAKMT2A
SCHEMBL27675916 0.78 LMNA (0.50) ALDH1A1LMNAGAAKMT2AELANE
SCHEMBL23027267 0.78 LTB4R (0.54) ALDH1A1HPGDLTB4RLTB4R2KMT2A
SCHEMBL563306 0.78 LTB4R (0.54) ALDH1A1HPGDLTB4RLTB4R2KMT2A
SCHEMBL13572924 0.78 LTB4R (0.54) ALDH1A1HPGDLTB4RLTB4R2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110483351-A The method for preparing thioesters by oxo thioacetic acid compound UNIV SCIENCE & TECHNOLOGY CHINA 2019-11-22 CN disclosed