Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28252471 | 0.87 | HTR6 (0.45) | HTR6KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL28584212 | 0.83 | ALDH1A1 (0.44) | KMT2AALDH1A1POLBSMN1; SMN2MAPT | |
| SCHEMBL1691772 | 0.80 | HTR6 (0.45) | HTR6KMT2AALDH1A1POLBHSD11B1 | |
| SCHEMBL28699989 | 0.80 | HTR6 (0.65) | HTR6KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL23303730 | 0.79 | HSD11B1 (0.44) | HTR6KMT2AALDH1A1POLBMAPT | |
| SCHEMBL1713160 | 0.78 | HTR6 (0.57) | HTR6KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL31092469 | 0.78 | HTR6 (0.57) | HTR6KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL4400959 | 0.78 | HTR6 (0.56) | HTR6KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL5454671 | 0.78 | HTR6 (0.46) | HTR6KMT2AALDH1A1POLBHSD11B1 | |
| SCHEMBL22028032 | 0.76 | POLB (0.50) | HTR6KMT2AALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110467572-A | The synthetic method of 3- sulfonyl-quinoline derivatives | UNIV WENZHOU | 2019-11-19 | — | — | CN | disclosed |