Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | MMP16 | P51512 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5451015 | 0.87 | HTR6 (0.65) | HTR6TP53RXFP1KDM4EPKM | |
| SCHEMBL28330197 | 0.80 | HTR6 (0.46) | HTR6KDM4EPKMKMT2AGAA | |
| SCHEMBL6913555 | 0.79 | HTR6 (1.00) | HTR6TP53RXFP1KDM4EPKM | |
| SCHEMBL1791418 | 0.78 | SMN1; SMN2 (0.50) | HTR6KDM4EPKMKMT2AGAA | |
| SCHEMBL6069944 | 0.76 | CA2 (0.50) | HTR6PKMALDH1A1 | |
| SCHEMBL2687430 | 0.76 | GSK3B (0.40) | HTR6PKMKMT2AGAAALDH1A1 | |
| SCHEMBL28078917 | 0.76 | TRPV4 (0.47) | HTR6TP53KDM4EPKMKMT2A | |
| SCHEMBL28252471 | 0.75 | HTR6 (0.45) | HTR6KDM4EPKMKMT2AABCC9 | |
| SCHEMBL1691772 | 0.75 | HTR6 (0.45) | HTR6FEN1KMT2AGAAALDH1A1 | |
| SCHEMBL2208523 | 0.74 | MEN1 (0.50) | KDM4EKMT2AHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127062-A | Thiadiazolyl derivatives as inhibitors of DNA polymerase Theta | 伊迪亚生物科学有限公司 | 2022-03-01 | — | — | CN | disclosed |