1-Naphthol

1-Naphthol

SCHEMBL28331151

CCC(=O)CC.Oc1cccc2ccccc12

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.65
IAPP P10997 2/20 0.46
GAA P10253 2/20 0.44
KMT2A Q03164 2/20 0.44
POLB P06746 1/20 0.44
ALDH1A1 P00352 2/20 0.43
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
KDM4E B2RXH2 1/20 0.43
GLA P06280 1/20 0.43
MEN1 O00255 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
NR4A1 P22736 1/20 0.42
NR4A2 P43354 1/20 0.42
NR4A3 Q92570 1/20 0.42
CNR2 P34972 1/20 0.42
PTPN1 P18031 1/20 0.42
PLK1 P53350 1/20 0.42
EPHX1 P07099 1/20 0.41
CDC25B P30305 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Naphthol SCHEMBL8045005 0.89 CYP1A2 (0.65) CYP1A2GAAKMT2APOLBALDH1A1
1-Naphthol SCHEMBL28476693 0.86 CYP1A2 (0.74) CYP1A2GAAKMT2APOLBALDH1A1
1-Naphthol SCHEMBL2481329 0.84 CYP1A2 (0.77) CYP1A2GAAKMT2APOLBALDH1A1
1-Naphthol SCHEMBL27983786 0.82 CYP1A2 (0.74) CYP1A2GAAPOLBALDH1A1HPGD
1-Naphthol SCHEMBL27970292 0.82 CYP1A2 (0.74) CYP1A2GAAKMT2APOLBALDH1A1
1-Naphthol SCHEMBL1656111 0.82 CYP1A2 (0.74) CYP1A2GAAKMT2APOLBALDH1A1
1-Naphthol SCHEMBL9450887 0.81 CYP1A2 (0.61) CYP1A2IAPPGAAKMT2AALDH1A1
1-Naphthol SCHEMBL7522683 0.81 CYP1A2 (0.81) CYP1A2GAAKMT2APOLBALDH1A1
1-Naphthol SCHEMBL10627914 0.81 CYP1A2 (0.90) CYP1A2POLBALDH1A1HPGDHSD17B10
1-Naphthol SCHEMBL273260 0.81 CYP1A2 (1.00) CYP1A2POLBALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110511233-A A kind of thiazole simultaneously [2,3-b] oxazole ketone compounds and its preparation method and application UNIV CHENGDU 2019-11-29 CN disclosed