Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Naphthol SCHEMBL9450887 | 0.89 | CYP1A2 (0.61) | CYP1A2TDP1KDM4EALDH1A1HPGD | |
| 1-Naphthol SCHEMBL28331151 | 0.89 | CYP1A2 (0.65) | CYP1A2TDP1KDM4EALDH1A1HPGD | |
| 1-Naphthol SCHEMBL11370302 | 0.86 | CYP1A2 (0.68) | CYP1A2TDP1KDM4EALDH1A1HPGD | |
| 1-Naphthol SCHEMBL28476693 | 0.86 | CYP1A2 (0.74) | CYP1A2TDP1KDM4EALDH1A1HPGD | |
| 1-Naphthol SCHEMBL1656111 | 0.86 | CYP1A2 (0.74) | CYP1A2TDP1KDM4EALDH1A1HPGD | |
| 1-Naphthol SCHEMBL7522683 | 0.86 | CYP1A2 (0.81) | CYP1A2TDP1KDM4EALDH1A1HPGD | |
| 1-Naphthol SCHEMBL28596585 | 0.85 | CYP1A2 (0.65) | CYP1A2TDP1KDM4EALDH1A1HPGD | |
| 1-Naphthol SCHEMBL28942248 | 0.84 | CYP1A2 (0.55) | CYP1A2TDP1KDM4EALDH1A1HPGD | |
| 1-Naphthol SCHEMBL2481329 | 0.84 | CYP1A2 (0.77) | CYP1A2TDP1KDM4EALDH1A1HPGD | |
| Phenanthrene SCHEMBL9560887 | 0.84 | ALDH1A1 (0.55) | CYP1A2TDP1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1100144-A | — | — | None | — | — | JP | disclosed |
| CN-105586326-B | Esterase and application thereof | 江南大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-105543253-B | Esterase and application thereof | 江南大学 | 2020-05-08 | — | — | CN | disclosed |
| CN-105695431-B | Esterase and application thereof | 江南大学 | 2020-05-08 | — | — | CN | disclosed |
| CN-105821059-B | Esterase and application thereof | 江南大学 | 2020-03-24 | — | — | CN | disclosed |
| EP-0825172-B1 | Synthesis of 1-acetoxy-2-methylnaphthalene | BRISTOL MYERS SQUIBB CO (US) | 2000-04-26 | — | — | EP | disclosed |
| EP-0825172-A1 | Synthesis of 1-acetoxy-2-methylnaphthalene | Bristol-Myers Squibb Company (US) | 1998-02-25 | — | — | EP | disclosed |
| US-5670698-A | Synthesis of 1-acetoxy-2-methylnaphthalene | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-09-23 | — | — | US | disclosed |
| US-5250693-A | Lipoxygenase inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-10-05 | — | — | US | disclosed |
| US-5208344-A | Benzothiazole derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-05-04 | — | — | US | disclosed |
| US-5084575-A | Drugs for the treatment of rhinitis, asthma and skin disorders | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-01-28 | — | — | US | disclosed |
| US-4960892-A | ENZYME INHIBITOR | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |
| JP-H01100144-A | NAPHTHALENEPROPIONIC ACID DERIVATIVE FOR ANTI-INFLAMMATORY/ANTI-ALLERGIC AGENT | AMERICAN HOME PROD CORP | 1989-04-18 | — | — | JP | disclosed |