Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | FPR3 | P25089 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | PDE8B | O95263 | 1/20 | 0.41 |
| ▸ | IL1B | P01584 | 1/20 | 0.41 |
| ▸ | AHCY | P23526 | 1/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28153227 | 0.84 | KDM1A (0.50) | KDM1APRMT5OPRD1LMNAALDH1A1 | |
| SCHEMBL5337684 | 0.81 | PRMT5 (0.53) | KDM1APRMT5OPRD1LMNAALDH1A1 | |
| SCHEMBL12311356 | 0.80 | OPRD1 (0.53) | KDM1APRMT5OPRD1LMNAALDH1A1 | |
| SCHEMBL31437092 | 0.80 | KDM1A (0.52) | KDM1APRMT5OPRD1LMNAALDH1A1 | |
| SCHEMBL15891825 | 0.80 | ALDH1A1 (0.52) | KDM1APRMT5OPRD1ALDH1A1FPR3 | |
| SCHEMBL16333400 | 0.80 | KDM1A (0.49) | KDM1APRMT5OPRD1ALDH1A1FPR3 | |
| SCHEMBL31515502 | 0.78 | LMNA (0.63) | LMNAALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL18487506 | 0.78 | LMNA (0.63) | LMNAALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL29939753 | 0.78 | NPC1 (0.48) | KDM1APRMT5OPRD1ALDH1A1FPR3 | |
| SCHEMBL5654694 | 0.78 | KDM1A (0.50) | KDM1APRMT5OPRD1ALDH1A1FPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928126-B | Amide derivative, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2019-12-20 | — | — | CN | disclosed |