Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR7 | P34969 | 3/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2834983 | 0.91 | HTR1A (0.34) | HTR1AS1PR1S1PR3ALDH1A1 | |
| SCHEMBL2833730 | 0.88 | HTR1A (0.36) | HTR1AKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL2830403 | 0.84 | TP53 (0.36) | HTR1AMEN1ALDH1A1KMT2A | |
| SCHEMBL2836813 | 0.84 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL2831164 | 0.83 | HTR1A (0.33) | HTR1AS1PR1S1PR3HTR2AHTR7 | |
| SCHEMBL2831056 | 0.83 | THRA (0.31) | S1PR1KMT2A | |
| SCHEMBL2829232 | 0.82 | S1PR1 (0.34) | HTR1AS1PR1S1PR3ALDH1A1 | |
| SCHEMBL2831013 | 0.82 | HTR1A (0.33) | HTR1AS1PR1S1PR3 | |
| SCHEMBL2830421 | 0.82 | CYP3A4 (0.40) | MEN1KMT2A | |
| SCHEMBL2832786 | 0.79 | CYP3A4 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160555-A1 | RESIN COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-24 | — | — | US | disclosed |
| EP-2133380-A1 | RESIN COMPOSITION | Sumitomo Chemical Company, Limited (JP) | 2009-12-16 | — | — | EP | disclosed |