Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2834983 | 0.88 | HTR1A (0.34) | HTR1AALDH1A1 | |
| SCHEMBL2833309 | 0.88 | HTR1A (0.37) | HTR1AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2830403 | 0.87 | TP53 (0.36) | HTR1AALDH1A1MEN1KMT2ANR1I2 | |
| SCHEMBL2831123 | 0.84 | SRD5A2 (0.35) | ALDH1A1KDM4E | |
| SCHEMBL2836033 | 0.82 | — | — | |
| SCHEMBL2832943 | 0.82 | HTR1A (0.32) | HTR1ANR1I2CYP3A4CYP2D6 | |
| SCHEMBL2828927 | 0.81 | HTR1A (0.32) | HTR1ANR1I2CYP3A4CYP2D6THRA | |
| SCHEMBL2831311 | 0.81 | THRB (0.33) | HTR1AALDH1A1KDM4ENR1I2CYP3A4 | |
| SCHEMBL2836817 | 0.81 | CYP3A4 (0.41) | CYP3A4CYP2D6 | |
| SCHEMBL2832747 | 0.78 | CYP3A4 (0.32) | CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160555-A1 | RESIN COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-24 | — | — | US | disclosed |
| EP-2133380-A1 | RESIN COMPOSITION | Sumitomo Chemical Company, Limited (JP) | 2009-12-16 | — | — | EP | disclosed |