Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 4/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28333131 | 1.00 | PDE2A (0.37) | PDE2AGPR3FFAR4ADORA2AFBP1 | |
| SCHEMBL28338194 | 0.85 | AMY1A (0.46) | AMY1ANPC1RAB9ALMNACYP1A2 | |
| SCHEMBL23070808 | 0.79 | NFE2L2 (0.41) | RAB9ALMNAGAA | |
| SCHEMBL23070810 | 0.79 | NFE2L2 (0.41) | RAB9ALMNAGAA | |
| SCHEMBL28094044 | 0.78 | BACE1 (0.39) | PDE2AGAASMN1; SMN2KIF11 | |
| SCHEMBL28094043 | 0.78 | BACE1 (0.39) | PDE2AGAASMN1; SMN2KIF11 | |
| SCHEMBL28175050 | 0.77 | MEN1 (0.39) | PDE2ANPC1RAB9ALMNAGAA | |
| SCHEMBL19634050 | 0.77 | KDM4E (0.41) | AMY1ALMNAGAA | |
| SCHEMBL30608104 | 0.77 | AMY1A (0.34) | AMY1ANPC1RAB9ALMNAHSD17B10 | |
| SCHEMBL28175049 | 0.77 | MEN1 (0.39) | PDE2ANPC1RAB9ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520423-A | AMINOTRIAZOLOPYRIDINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO | 2019-11-29 | — | — | CN | disclosed |