SCHEMBL28333502

SCHEMBL28333502

CCC(C)(C)C1=C(C2=C(C(C)(C)CC)C(=O)c3ccccc3C2=O)C(=O)c2ccccc2C1=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 11/20 0.56
▸ SMN1; SMN2 Q16637 10/20 0.56
▸ NPC1 O15118 10/20 0.56
▸ LMNA P02545 5/20 0.56
▸ MAPK1 P28482 3/20 0.56
▸ CASP3 P42574 2/20 0.56
▸ SENP8 Q96LD8 2/20 0.56
▸ SENP7 Q9BQF6 2/20 0.56
▸ SENP6 Q9GZR1 2/20 0.56
▸ ATM Q13315 1/20 0.56
▸ MAPT P10636 12/20 0.43
▸ ALDH1A1 P00352 12/20 0.43
▸ TP53 P04637 5/20 0.43
▸ MAPK10 P53779 4/20 0.43
▸ PKM P14618 3/20 0.43
▸ GLA P06280 1/20 0.43
▸ GAA P10253 1/20 0.43
▸ KLF5 Q13887 1/20 0.43
▸ MEN1 O00255 5/20 0.42
▸ KMT2A Q03164 5/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8405065 0.83 APAF1 (0.52) RAB9ASMN1; SMN2NPC1LMNAMAPK1
SCHEMBL8459717 0.77 LMNA (0.45) RAB9ASMN1; SMN2NPC1LMNAMAPK1
Anthraquinone SCHEMBL28722242 0.76 RAB9A (0.71) RAB9ASMN1; SMN2NPC1LMNAMAPK1
SCHEMBL29399456 0.75 LMNA (0.47) RAB9ASMN1; SMN2NPC1LMNAMAPK1
SCHEMBL395873 0.75 LMNA (0.47) RAB9ASMN1; SMN2NPC1LMNAMAPK1
SCHEMBL187755 0.72 NPC1 (1.00) RAB9ASMN1; SMN2NPC1LMNAMAPK1
SCHEMBL29482674 0.72 NPC1 (1.00) RAB9ASMN1; SMN2NPC1LMNAMAPK1
SCHEMBL1138203 0.72 LMNA (0.60) RAB9ASMN1; SMN2NPC1LMNAMAPK1
SCHEMBL12023693 0.72 RAB9A (0.51) RAB9ASMN1; SMN2NPC1LMNAMAPK1
SCHEMBL7095845 0.71 HSP90AA1 (0.51) RAB9ASMN1; SMN2NPC1LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107132734-B Electrophotographic photoreceptor, process cartridge, and image forming apparatus 富士胶片商业创新有限公司 2022-06-10 — — CN disclosed
CN-105911822-B Electrophotographic photoreceptor, process cartridge, and image forming apparatus 富士施乐株式会社 2019-12-06 — — CN disclosed
Send feedback