SCHEMBL29399456

SCHEMBL29399456

CCC(C)(C)C1=C(C#N)C(=O)c2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.47
▸ NPC1 O15118 4/20 0.47
▸ RAB9A P51151 4/20 0.47
▸ SMN1; SMN2 Q16637 4/20 0.47
▸ MAPK1 P28482 3/20 0.47
▸ CASP3 P42574 2/20 0.47
▸ SENP8 Q96LD8 2/20 0.47
▸ SENP7 Q9BQF6 2/20 0.47
▸ SENP6 Q9GZR1 2/20 0.47
▸ ATM Q13315 1/20 0.47
▸ PARG Q86W56 1/20 0.38
▸ USP8 P40818 3/20 0.38
▸ USP7 Q93009 2/20 0.38
▸ USP47 Q96K76 1/20 0.36
▸ MCL1 Q07820 2/20 0.35
▸ BCL2 P10415 2/20 0.35
▸ ALDH1A1 P00352 5/20 0.35
▸ MAPT P10636 5/20 0.35
▸ POLB P06746 2/20 0.35
▸ HTT P42858 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL395873 1.00 LMNA (0.47) LMNANPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL28333502 0.75 RAB9A (0.56) LMNANPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL29496222 0.74 MEN1 (0.55) LMNANPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL187098 0.74 MEN1 (0.55) LMNANPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL10696799 0.72 RAB9A (0.39) LMNANPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL8405065 0.71 APAF1 (0.52) LMNANPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL28383679 0.70 USP8 (0.50) LMNANPC1RAB9ASMN1; SMN2MAPK1
Anthraquinone SCHEMBL28722242 0.68 RAB9A (0.71) LMNANPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL10967500 0.67 ALDH1A1 (0.50) LMNASMN1; SMN2USP8USP7USP47
SCHEMBL7854282 0.67 USP8 (0.37) LMNANPC1RAB9ASMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12391729-B2 Fusion proteins, recombinant bacteria, and methods for using recombinant bacteria SPOGEN BIOTECH INC. (US) 2025-08-19 — — US claimed
US-20240199709-A1 FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA SPOGEN BIOTECH INC (US) 2024-06-20 — — US claimed
US-11905315-B2 Fusion proteins, recombinant bacteria, and methods for using recombinant bacteria SPOGEN BIOTECH INC. (US) 2024-02-20 — — US claimed
US-12630484-B2 Methods for promoting plant health using free enzymes and microorganisms that overexpress enzymes SPOGEN BIOTECH INC. (US) 2026-05-19 — — US disclosed
US-12599649-B2 Bioactive polypeptides for improvements in plant protection, growth and productivity SPOGEN BIOTECH INC. (US) 2026-04-14 — — US disclosed
US-12599141-B2 Rod-shaped plant viral nanoparticles or virus-like particles for agricultural applications CASE WESTERN RESERVE UNIVERSITY (US) 2026-04-14 — — US disclosed
US-20250388630-A1 FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA SPOGEN BIOTECH INC (US) 2025-12-25 — — US disclosed
US-20250351825-A1 AGRICULTURAL COMPOSITIONS FOR PROTECTING PLANTS AGAINST ABIOTIC STRESSORS SPOGEN BIOTECH INC (US) 2025-11-20 — — US disclosed
US-20250324980-A1 COMPOSITIONS FOR DELIVERY OF AGENTS INTO PLANT CELLS OHIO STATE INNOVATION FOUNDATION (US) 2025-10-23 — — US disclosed
US-20250296896-A1 METHODS FOR PROMOTING PLANT HEALTH USING FREE ENZYMES AND MICROORGANISMS THAT OVEREXPRESS ENZYMES SPOGEN BIOTECH INC (US) 2025-09-25 — — US disclosed
US-20250296895-A1 METHODS FOR PROMOTING PLANT HEALTH USING FREE ENZYMES AND MICROORGANISMS THAT OVEREXPRESS ENZYMES SPOGEN BIOTECH INC (US) 2025-09-25 — — US disclosed
US-20230225315-A1 METHODS OF DELIVERING PLANT VIRUS-BASED NANOPESTICIDES UNIV CASE WESTERN RESERVE (US) 2023-07-20 — — US disclosed
US-11674150-B2 Genetically modified seed combined with spore forming bacterium and optional insect control agents and methods for treating plants BASF CORPORATION (US) 2023-06-13 — — US disclosed
US-20230134066-A1 METHODS FOR PROMOTING PLANT HEALTH USING FREE ENZYMES AND MICROORGANISMS THAT OVEREXPRESS ENZYMES SPOGEN BIOTECH INC (US) 2023-05-04 — — US disclosed
US-11589577-B2 Nanotechnology system for agricultural applications NORTH CAROLINA STATE UNIVERSITY (US) 2023-02-28 — — US disclosed
US-20230016543-A1 BIOACTIVE POLYPEPTIDES FOR IMPROVEMENTS IN PLANT PROTECTION, GROWTH AND PRODUCTIVITY GENISYS CREDIT UNION 2023-01-19 — — US disclosed
US-20220338470-A1 AGRICULTURAL COMPOSITIONS FOR IMPROVED CROP PRODUCTIVITY AND ENHANCED PHENOTYPES SPOGEN BIOTECH INC. 2022-10-27 — — US disclosed
US-20220135492-A1 METHODS FOR PROMOTING PLANT HEALTH USING FREE ENZYMES AND MICROORGANISMS THAT OVEREXPRESS ENZYMES GENISYS CREDIT UNION 2022-05-05 — — US disclosed
US-20220087268-A1 BIOACTIVE POLYPEPTIDES FOR IMPROVEMENTS IN PLANT PROTECTION, GROWTH AND PRODUCTIVITY GENISYS CREDIT UNION 2022-03-24 — — US disclosed
US-20220055961-A1 METHODS FOR PROMOTING PLANT HEALTH USING FREE ENZYMES AND MICROORGANISMS THAT OVEREXPRESS ENZYMES GENISYS CREDIT UNION 2022-02-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630484-B2 Methods for promoting plant health using free enzymes and microorganisms that overexpress enzymes ADA, RNGTT, GNPDA1 LMNA 3510/4885NPC1 4183/4885RAB9A 3873/4885
US-12599649-B2 Bioactive polypeptides for improvements in plant protection, growth and productivity MAX, VIP, MRTO4 LMNA 1747/4885NPC1 2510/4885RAB9A 863/4885
US-20250324980-A1 COMPOSITIONS FOR DELIVERY OF AGENTS INTO PLANT CELLS ARGLU1, PHAX, VMA21 LMNA 1496/4885NPC1 268/4885RAB9A 169/4885
US-11674150-B2 Genetically modified seed combined with spore forming bacterium and optional insect control agents and methods for treating plants GMNN, GMDS, DBF4 LMNA 2954/4885NPC1 4164/4885RAB9A 2583/4885
US-20250388630-A1 FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA MAX, SEC62, GHITM LMNA 3795/4885NPC1 4362/4885RAB9A 968/4885
US-12599141-B2 Rod-shaped plant viral nanoparticles or virus-like particles for agricultural applications PRNP, PCNP, VIM LMNA 273/4885NPC1 4344/4885RAB9A 1966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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