SCHEMBL28334244

SCHEMBL28334244

CC(C)(O)C#Cc1ccc(C2OCCO2)cc1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
TSHR P16473 1/20 0.39
ASIC3 Q9UHC3 1/20 0.38
LMNA P02545 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ALDH1A1 P00352 2/20 0.36
HTT P42858 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
GAA P10253 2/20 0.35
MAP3K14 Q99558 5/20 0.35
PIK3CD O00329 2/20 0.35
PIK3R1 P27986 2/20 0.35
HAO1 Q9UJM8 1/20 0.34
PTGES2 Q9H7Z7 2/20 0.34
MCL1 Q07820 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10553881 0.81 HAO1 (0.36) SMN1; SMN2TSHRASIC3LMNAALDH1A1
SCHEMBL12391039 0.78 ASIC3 (0.50) MAPTSMN1; SMN2TSHRASIC3LMNA
SCHEMBL13814772 0.77 GABRP (0.44) RAB9AKMT2A
SCHEMBL4018845 0.74 CCNB2 (0.35) RAB9AKMT2A
SCHEMBL9451016 0.71 MEN1 (0.44) MAPTSMN1; SMN2TSHRHTTNPC1
SCHEMBL14268091 0.70 ASIC3 (0.49) MAPTSMN1; SMN2TSHRASIC3LMNA
SCHEMBL12711667 0.70 APP (0.47) MAPTSMN1; SMN2TSHRASIC3LMNA
SCHEMBL19432766 0.70 L3MBTL1 (0.35) MAPTSMN1; SMN2TSHRASIC3LMNA
SCHEMBL6132631 0.69 MAPT (0.48) MAPTSMN1; SMN2TSHRASIC3ALDH1A1
SCHEMBL6132628 0.69 MAPT (0.48) MAPTSMN1; SMN2TSHRASIC3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110551076-A benzoxazole liquid crystal compound containing acetylene bonds and preparation method thereof UNIV SHAANXI NORMAL 2019-12-10 CN claimed
CN-117026296-A Composite material for photoelectrochemical water decomposition and preparation method and application thereof 陕西师范大学 2023-11-10 CN disclosed
CN-110551076-A benzoxazole liquid crystal compound containing acetylene bonds and preparation method thereof UNIV SHAANXI NORMAL 2019-12-10 CN disclosed