Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | TEC | P42680 | 1/20 | 0.47 |
| ▸ | TXK | P42681 | 1/20 | 0.47 |
| ▸ | BMX | P51813 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | ITK | Q08881 | 1/20 | 0.47 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28336807 | 0.81 | BTK (0.49) | BTKJAK2LCKTECTXK | |
| SCHEMBL29785261 | 0.77 | ALOX15 (0.58) | BTKJAK2LCKTECTXK | |
| SCHEMBL29564600 | 0.77 | ALOX15 (0.58) | BTKJAK2LCKTECTXK | |
| SCHEMBL28336845 | 0.74 | GFER (0.54) | BTK | |
| SCHEMBL18976056 | 0.72 | BTK (0.78) | BTKJAK2LCKTECTXK | |
| SCHEMBL28334523 | 0.69 | PABPC1 (0.36) | — | |
| SCHEMBL20303901 | 0.64 | BTK (0.52) | BTKJAK2 | |
| SCHEMBL11274877 | 0.64 | NR1H2 (0.41) | BTKJAK2 | |
| SCHEMBL28164562 | 0.63 | AHR (0.53) | BTKTECTXKBMXJAK3 | |
| SCHEMBL1375257 | 0.62 | NR1H2 (0.60) | BTKJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110312713-A | Process for preparing tetrahydrocarbazole carboxamide compounds | 百时美施贵宝公司 | 2019-10-08 | — | — | CN | disclosed |