Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28336845 | 0.79 | GFER (0.54) | PABPC1PARP14GFERMAPTALOX15 | |
| SCHEMBL27648564 | 0.71 | JAK2 (0.53) | PABPC1PARP14MAPTHSD17B10 | |
| SCHEMBL28905717 | 0.70 | PARP1 (0.54) | PABPC1CASP7HSD17B10TSHR | |
| SCHEMBL28334447 | 0.69 | BTK (0.47) | — | |
| SCHEMBL28164562 | 0.69 | AHR (0.53) | PABPC1PARP14MAPTMAPK1TSHR | |
| SCHEMBL29506423 | 0.67 | PABPC1 (0.59) | PABPC1MAPTALOX15HSD17B10TSHR | |
| SCHEMBL15453221 | 0.67 | PABPC1 (0.59) | PABPC1MAPTALOX15HSD17B10TSHR | |
| SCHEMBL28188584 | 0.67 | POLB (0.55) | PABPC1PARP14MAPT | |
| SCHEMBL28166021 | 0.66 | JAK2 (0.38) | PABPC1PARP14MAPT | |
| SCHEMBL28164437 | 0.63 | NR3C1 (0.56) | PABPC1MAPTMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110312713-A | Process for preparing tetrahydrocarbazole carboxamide compounds | 百时美施贵宝公司 | 2019-10-08 | — | — | CN | disclosed |