Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP12 | P39900 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901171 | 0.86 | MMP1 (0.53) | ALDH1A1MMP1MMP2MMP9MMP12 | |
| SCHEMBL27803787 | 0.80 | MMP1 (0.44) | ALDH1A1MMP1MMP2MMP9MMP12 | |
| SCHEMBL28740447 | 0.80 | NQO1 (0.42) | ALDH1A1MMP1MMP2MMP9MMP12 | |
| SCHEMBL28740381 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TDP1MEN1KMT2AKDM4E | |
| SCHEMBL29668885 | 0.78 | SCN1A (0.40) | ALDH1A1MMP1MMP2MMP9MMP12 | |
| SCHEMBL28740265 | 0.78 | RIPK1 (0.40) | ALDH1A1MMP1MMP2MMP9MMP12 | |
| SCHEMBL30211075 | 0.78 | ALDH1A1 (0.64) | ALDH1A1MMP1MMP2MMP9MMP12 | |
| SCHEMBL5766366 | 0.78 | ALDH1A1 (0.64) | ALDH1A1MMP1MMP2MMP9MMP12 | |
| SCHEMBL28337762 | 0.77 | RIPK1 (0.39) | ALDH1A1MMP1MMP2MMP9MMP12 | |
| SCHEMBL28686546 | 0.76 | SMN1; SMN2 (0.46) | ALDH1A1MMP1MMP2MMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325531-B | Benzenesulfonamides and their use as therapeutic agents | 泽农医药公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-110325531-A | Benzsulfamide and its purposes as therapeutic agent | 泽农医药公司 | 2019-10-11 | — | — | CN | disclosed |