SCHEMBL2833652

SCHEMBL2833652

CCCC(C)(C)C(=O)N(Cc1ccccc1)C(CC)c1ccc(F)c([Ti](C2=CC=CC2)(C2=CC=CC2)c2c(F)ccc(C(CC)N(Cc3ccccc3)C(=O)C(C)(C)CCC)c2F)c1F

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 1/20 0.35
RIPK1 Q13546 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL482535 0.82 RIPK1 (0.38) RIPK1
SCHEMBL2833657 0.78 MC4R (0.34) RIPK1
SCHEMBL482766 0.76 MLYCD (0.33) RIPK1
SCHEMBL483092 0.74 RIPK1 (0.31) RIPK1
SCHEMBL483042 0.74 POLB (0.40) TRPM8RIPK1
SCHEMBL5179845 0.73 MLYCD (0.34)
SCHEMBL270458 0.73 S1PR1 (0.33) RIPK1
SCHEMBL2830157 0.72 KIF11 (0.36) TRPM8
SCHEMBL483195 0.72 RIPK1 (0.31) RIPK1
SCHEMBL482923 0.71 MEN1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741005-B2 A planographic printing plate precursor comprising: an aluminum support; and a photosensitive layer including a polymerization initiator, a polymerizable compound and a binder polymer; an oxygen barrier layer; and a protective layer including a filler; capable of image formation FUJIFILM CORPORATION (JP) 2010-06-22 US disclosed
EP-1839853-B1 Planographic printing plate precursor and stack thereof FUJIFILM CORP (JP) 2009-07-08 EP disclosed
US-20070231740-A1 A planographic printing plate precursor comprising: an aluminum support; and a photosensitive layer including a polymerization initiator, a polymerizable compound and a binder polymer; an oxygen barrier layer; and a protective layer including a filler; capable of image formation FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
EP-1839853-A1 Planographic printing plate precursor and stack thereof FUJIFILM Corporation (JP) 2007-10-03 EP disclosed