SCHEMBL2833655

SCHEMBL2833655

CCCC(C)(C)C(=O)N(Cc1ccccc1F)CC(F)Cc1ccccc1[Ti](C1=CC=CC1)(C1=CC=CC1)c1ccccc1CC(F)CN(Cc1ccccc1F)C(=O)C(C)(C)CCC

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 3/20 0.38
LMNA P02545 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 2/20 0.32
SLC6A2 P23975 2/20 0.32
SLC6A3 Q01959 2/20 0.32
TSPO P30536 1/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2833726 0.74
SCHEMBL2830159 0.73 ALDH1A1 (0.33) ALDH1A1
SCHEMBL9800261 0.67 RIPK1 (0.37) RIPK1
SCHEMBL2833657 0.66 MC4R (0.34) RIPK1
SCHEMBL9155821 0.66 GABRA1 (0.35) LMNANPSR1MAPT
SCHEMBL6553855 0.66 RIPK1 (0.35) RIPK1
SCHEMBL9800169 0.65 RIPK1 (0.35) RIPK1
SCHEMBL482535 0.64 RIPK1 (0.38) RIPK1LMNA
SCHEMBL483092 0.63 RIPK1 (0.31) RIPK1
SCHEMBL17882322 0.63 RIPK1 (0.72) RIPK1ALDH1A1TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741005-B2 A planographic printing plate precursor comprising: an aluminum support; and a photosensitive layer including a polymerization initiator, a polymerizable compound and a binder polymer; an oxygen barrier layer; and a protective layer including a filler; capable of image formation FUJIFILM CORPORATION (JP) 2010-06-22 US disclosed
EP-1839853-B1 Planographic printing plate precursor and stack thereof FUJIFILM CORP (JP) 2009-07-08 EP disclosed
US-20070231740-A1 A planographic printing plate precursor comprising: an aluminum support; and a photosensitive layer including a polymerization initiator, a polymerizable compound and a binder polymer; an oxygen barrier layer; and a protective layer including a filler; capable of image formation FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
EP-1839853-A1 Planographic printing plate precursor and stack thereof FUJIFILM Corporation (JP) 2007-10-03 EP disclosed