SCHEMBL28337779

SCHEMBL28337779

Cc1cccc(N)c1C(=O)O.O=C(OC(=O)C(F)(F)F)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CD44 P16070 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
MYC P01106 1/20 0.35
ESR1 P03372 1/20 0.35
KCNH2 Q12809 1/20 0.35
KDM4E B2RXH2 3/20 0.34
HSD17B10 Q99714 3/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
MMP2 P08253 1/20 0.34
KMT2A Q03164 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL221626 0.83 TDP1 (0.52) TDP1L3MBTL1CD44CA12CA1
Hydrochloric Acid SCHEMBL7442929 0.82 TDP1 (0.50) TDP1L3MBTL1CD44CA12CA1
SCHEMBL28337781 0.79 MYC (0.45) TDP1CD44MYCKDM4EHSD17B10
Acetaldehyde SCHEMBL28045568 0.77 TDP1 (0.46) TDP1L3MBTL1CD44CA12CA1
SCHEMBL18209596 0.73 CD44 (0.45) TDP1L3MBTL1CD44CA12CA1
SCHEMBL10434368 0.73 KDM4E (0.50) TDP1L3MBTL1CD44MYCKDM4E
Toluene SCHEMBL27497852 0.71 ACHE (0.46) CA2ALDH1A1KMT2AMEN1POLB
Salicylic Acid SCHEMBL8206594 0.71 ALDH1A1 (0.56) TDP1CA12CA1CA2CA7
Trifluoroacetic Acid SCHEMBL2160348 0.70 CYP3A4 (0.46) TDP1CD44MYCESR1KCNH2
SCHEMBL1000014 0.70 MMP2 (0.54) TDP1CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110447651-A A kind of quianzolinones and the application in preparation or prevention and treatment agricultural plant disease UNIV LANZHOU 2019-11-15 CN disclosed